The processing of fruits results in generation of high amounts of waste materials such as peels, seeds, stones, pomace, rags, kernels and oilseed meals A disposal of these materials in the environment usually represents a problem that is further aggravated by legal restrictions. But, significant quantities of fruit peels (20- 30% for banana and 30 -50% for mango) are discarded as waste by the processing industries which cause a real environmental problems Peels are the major by-products obtained during the processing of various fruits and these have been shown to be a good source of various bioactive compounds which posses various beneficial effects. It is well known that, by-products represent an important source of sugars, minerals, organic acid, dietary fibre and phenolics which have a wide range of action which includes antitumoral, antiviral, antibacterial, cardioprotective and antimutagenic activities. Thus, new aspects concerning the use of these wastes as by-products for further exploitation on the production of food additives or supplements with high nutritional value have gained increasing interest because these are high-value products and their recovery may be economically attractive... Natural products provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Use of local resources and crop by-products as livestock feeds is a necessary precondition for profitable production. Several by-products have potential value, especially for ruminants, due to their ability to digest fibre. Because of increasing threat of infectious diseases, the need of the hour is to find natural agents with novel mechanism of action. It is well known that by-products represent an important source of sugars, minerals, organic acid, dietary fibre and phenolics which have a wide range of action which includes antitumoral, antiviral, antibacterial, cardioprotective and antimutagenic activities. Thus, Peels are the major by-products obtained during the processing of various fruits and these were shown to be a good source of various bioactive compounds which posses various beneficial effects. But, significant quantities of fruit peels (20- 30% for banana and 30 -50% for mango) are discarded as waste by the processing industries which cause a real environmental problems (Zhang et al. 2005). A disposal of these materials in the environment usually represents a problem that is further aggravated by legal restrictions.